The pharyngeal nervous system orchestrates feeding behavior in planarians
2020年4月8日 · Here, we use the freshwater planarian Dugesia japonica to show that an isolated pharynx amputated from the planarian body self-directedly executes its entire sequence of feeding functions: food sensing, approach, decisions about ingestion, and intake. Gene-specific silencing experiments by RNA interference demonstrated that the pharyngeal ...
Planarian - Wikipedia
Planarians are bilaterian flatworms that lack a fluid-filled body cavity, and the space between their organ systems is filled with parenchyma. [5] [13] Planarians lack a circulatory system, and absorb oxygen through their body wall. They uptake food to their gut using a muscular pharynx, and nutrients diffuse to internal tissues.
Planarian stem cells sense the identity of the missing pharynx to ...
2021年6月22日 · Planarian stem cells respond to organ loss by selectively increasing expression of organ-specific transcription factors required for subsequent regeneration. Amputation of non-pharyngeal tissues only amplifies non-pharyngeal progenitors, while removal of pharynx tissue selectively increases pharynx progenitors.
Planarian stem cells sense the identity of the missing pharynx to ...
2021年6月22日 · Planarian flatworms have an extensive stem cell population responsible for regenerating any organ after amputation. Here, we compare planarian stem cell responses to different injuries by either amputation of a single organ, the pharynx, or removal of tissues from other organs by decapitation.
Chemical Amputation and Regeneration of the Pharynx in the Planarian
2018年3月26日 · In this manuscript, we describe a method to selectively ablate an entire organ called the pharynx in the planarian Schmidtea mediterranea. Planarians are a classical model of regeneration, known for their prolific regenerative ability, where even minute fragments can regrow whole animals 7,8.
Planaria: Genes for regeneration - eLife
2014年4月15日 · Here we describe a single-organ regeneration assay in which ejection of the planarian pharynx is selectively induced by brief exposure of animals to sodium azide. To identify genes required for pharynx regeneration, we performed an RNAi screen of 356 genes upregulated after amputation, using successful feeding as a proxy for regeneration.
Planarian pharynx regeneration revealed by the expression of …
We examined the process of regeneration of the pharynx in the planarian Dugesia japonica in detail by in situ hybridization and immunohistochemistry for myosin heavy chain-A (DjMHC-A), which is mainly expressed in the pharynx muscles and pharynx-anchoring muscles.
Pharynx regeneration in planarians | Russian Journal of …
2009年2月14日 · The obtained and published data on pharynx regeneration in planarians have been reviewed. Planarians can regenerate from a small body fragment and restore all missing organs including the pharynx. The pharynx is a relatively autonomous organ with a differentiated structure and specialized function.
The Process of Pharynx Regeneration in Planarians
1999年7月1日 · To understand the cellular events during planarian regeneration, we analyzed the process of pharynx regeneration in both head and tail pieces using cell-type-specific markers. Interestingly, cells expressing the pharynx-muscle-specific myosin heavy chain gene ( DjMHC-A) appeared within 24 h after amputation (prior to the formation of a pharynx ...
Pla-narians can regenerate from a small body fragment and restore all missing organs including the pharynx. The pharynx is a relatively autonomous organ with a differentiated structure and specialized function. Pharynx regeneration has specific features, and its studies are of considerable theoretical interest.