Sublingual administration - Wikipedia
A relatively new way of administration of therapeutic peptides and proteins (such as cytokines, domain antibodies, Fab fragments or single chain antibodies) is sublingual administration. Peptides and proteins are not stable in the gastro-intestinal tract, mainly due to degradation by enzymes and pH differences.
Medication Routes of Administration - StatPearls - NCBI Bookshelf
2023年8月23日 · A sublingual or buccal route is another form of the enteral route of medication administration that offers the benefit of bypassing the first-pass effect. By applying the drug directly under the tongue (sublingual) or on the cheek (buccal), the medication undergoes a passive diffusion through the venous blood in the oral cavity, which bypasses ...
Sublingual Administration Guide: Examples and Definition - GoodRx
2023年2月15日 · Sublingually administered medications are dissolved underneath the tongue before passing directly into the bloodstream. Unlike traditional oral medications, they don’t have to pass through the GI tract or liver. This means they work quickly and aren’t affected by how well the GI tract or liver works.
Sublingual Administration - an overview | ScienceDirect Topics
2011年11月23日 · Sublingual administration of drug refers to the placement of drug under the tongue (Rehfeld et al., 2017). The sublingual route bypasses the first-pass metabolism and hence facilitates rapid absorption of the drug into the systemic circulation. Drug directly reaches the systemic circulation using blood vessels.
How to Administer Sublingual Medication: 13 Steps (with Pictures) - wikiHow
2024年8月4日 · Doctors may recommend sublingual medications to treat certain conditions, or if a patient has trouble swallowing or digesting medication. Understanding how to administer sublingual medication can help ensure proper dosing and efficacy of the medication.
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Sublingual Route - an overview | ScienceDirect Topics
Sublingual administration, in which a tablet or troche is allowed to dissolve completely in the oral cavity, takes advantage of the permeability of the oral epithelium and is the preferred route for a few potent lipophilic drugs, such as nitroglycerin and oxytocin, and even the commonly used oral sedative triazolam.
Sublingual and Buccal Medication Administration - Healthline
2017年6月7日 · Sublingual administration involves placing a drug under your tongue to dissolve and absorb into your blood through the tissue there. Buccal administration involves placing a...
Sublingual Administration - an overview | ScienceDirect Topics
Certain drugs can be administered sublingually (i.e., they can be absorbed into the blood through the mucous membranes of the oral cavity). Examples of the clinical use of sublingual drug administration include nitroglycerin for management of anginal pain, 24 aspirin in the prehospital management of suspected myocardial infarction victims, 25 ...
Sublingual Route of Drug Delivery | SpringerLink
2021年10月8日 · Sublingual drug administration is the process of placing a dosage form (usually tablets, lozenges, or strips) under the tongue where it dissolves completely, allowing the drug to directly reach systemic blood circulation upon absorption. Sublingual drops and sprays are also administered via this route.
Understanding the Routes of Administration | SpringerLink
2022年4月8日 · Deepak Gupta, Sheeba Varghese Gupta & Ningning Yang. 1167 Accesses. Abstract. Routes of administration are the key determinant to ensuring therapeutic benefits of the drug. The choice of route of drug delivery is vastly dependent on drug properties, disease states, site of action, and patient compliance.
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