Sickle cell disease - Wikipedia
Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] . The most common type is known as sickle cell anemia. [2] . It …
Sickle Cell Disease (SCD): Types, Symptoms & Causes - Cleveland Clinic
Sickle cell disease affects the hemoglobin within your red blood cells. A genetic mutation causes abnormal hemoglobin to clump together, causing the red blood cells to turn sickle shaped. …
About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC
2024年11月7日 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood …
Sickle Cell Disease - Johns Hopkins Medicine
Sickle cell disease is a blood disorder in which the hemoglobin is damaged and can't carry oxygen to the tissues. These blood cells with the defective hemoglobin are sticky and can build up and …
Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
2024年9月30日 · Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow …
Sickle cell anemia - Symptoms & causes - Mayo Clinic
2022年12月22日 · Sickle cell anemia is caused by a change in the gene that tells the body to make hemoglobin. Hemoglobin is the iron-rich compound in red blood cells that allows these …
Sickle Cell Disease - Sickle Cell Disease - The Merck Manuals
Sickle cell disease is an inherited genetic abnormality of hemoglobin (the oxygen-carrying protein found in red blood cells) characterized by sickle (crescent)-shaped red blood cells and chronic …
What to know about sickle cell anemia and hemoglobin - Medical News Today
2022年7月30日 · Sickle cell disease (SCD) is a genetic disorder that causes red blood cells to take the shape of a sickle or a letter “C.” Levels of hemoglobin, a protein that helps carry …
Sickle Cell Disease—Genetics, Pathophysiology, Clinical …
Sickle cell disease (SCD) is a monogenetic disorder due to a single base-pair point mutation in the β-globin gene resulting in the substitution of the amino acid valine for glutamic acid in the β …
Sickle cell disease - Nature Reviews Disease Primers
2018年3月15日 · Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB, which encodes haemoglobin subunit β. The incidence is estimated to be between …