Peroxisome proliferator-activated receptor alpha - Wikipedia
Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a …
PPARα: An emerging target of metabolic syndrome, …
Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor that is involved in lipid metabolism of various tissues. Different metabolites of fatty acids and …
Peroxisome proliferator-activated receptor - Wikipedia
The first PPAR (PPARα) was discovered in 1990 during the search for a molecular target of a group of agents then referred to as peroxisome proliferators, as they increased peroxisomal …
The peroxisome proliferator-activated receptor: A family of …
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of nuclear hormone receptor superfamily comprising of the following three subtypes: PPARα, …
Integrated physiology and systems biology of PPARα
2014年7月1日 · The Peroxisome Proliferator Activated Receptor alpha (PPARα) is a transcription factor that plays a major role in metabolic regulation. This review addresses the functional role …
PPARs: regulators of metabolism and as therapeutic targets in ...
Since PPARα is a master regulator of genes involved in lipoprotein and triglyceride metabolism, in particular β-oxidation, cellular uptake and export of fatty acids, future directions should be …
Molecular mechanism of PPARα action and its impact on lipid …
2015年3月1日 · Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor belonging, together with PPARγ and PPARβ/δ, to the NR1C nuclear …
PPAR control of metabolism and cardiovascular functions
2021年6月14日 · PPARα increases cellular fatty acid uptake, esterification and trafficking, and regulates lipoprotein metabolism genes. PPARδ stimulates lipid and glucose utilization by …
PPARα: An emerging target of metabolic syndrome ... - PubMed
2022年12月16日 · Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor that is involved in lipid metabolism of various tissues. Different metabolites …
PPARα activation promotes liver progenitor cell-mediated liver ...
2023年10月25日 · Using the zebrafish model of LPC-mediated liver regeneration, Tg (fabp10a:pt-β-catenin), we present that peroxisome proliferator-activated receptor-alpha (PPARα) …