Hedgehog signaling pathway - Wikipedia
The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different parts of the embryo have different concentrations of hedgehog signaling proteins.
The mechanisms of Hedgehog signalling and its roles in ...
2013年5月30日 · The Hedgehog signalling pathway has diverse functions in animal development and tissue homeostasis. Dysregulation of the pathway has been implicated in several developmental syndromes and...
Hedgehog Signaling - Cell Signaling Technology
The evolutionarily conserved Hedgehog (Hh) pathway is essential for normal embryonic development and plays critical roles in adult tissue maintenance, renewal and regeneration. Secreted Hh proteins act in a concentration- and time-dependent manner to initiate a series of cellular responses that range from survival and proliferation to cell fate ...
Hedgehog signaling in tissue homeostasis, cancers and ...
2023年8月18日 · HH signaling pathway has important functions in embryonic development and tissue homeostasis. It plays a central role in the regulation of the proliferation and differentiation of adult stem...
Cellular and molecular mechanisms of Hedgehog signalling
2023年3月17日 · Here we discuss the mechanisms of Hedgehog signalling, focusing on recent advances in understanding the molecular basis of mammalian Hedgehog signal transduction at the cell membrane....
Sonic hedgehog signalling pathway: a complex network - PMC
Sonic Hedgehog (Shh) signalling cascade is one of the intricate signal transduction mechanisms that govern the precisely regulated developmental processes of multicellular organisms.
Cellular and molecular mechanisms of Hedgehog signalling
The Hedgehog signalling pathway has crucial roles in embryonic tissue patterning, postembryonic tissue regeneration, and cancer, yet aspects of Hedgehog signal transmission and reception have until recently remained unclear.