Fibronectin - Wikipedia
Fibronectin is a high-molecular weight (~500-~600 kDa) [5] glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. [6] Fibronectin also binds …
Fibronectin - an overview | ScienceDirect Topics
Fibronectin is an extracellular glycoprotein that helps organize and maintain homeostasis of the extracellular matrix [93]. Fibronectin binds to collagen, functions in cell adhesion, migration, …
Fibronectin: Molecular Structure, Fibrillar Structure and ... - PubMed
2021年9月16日 · In this review, we will discuss the assembly of FN fibrils from individual FN molecules; the composition, structure, and mechanics of FN fibrils; the interaction of FN fibrils …
13.4: Fibronectins - Biology LibreTexts
Fibronectin is formed by the joining of two similar polypeptide subunits via a pair of disulfide bonds near the C-terminal of each (Figure \(\PageIndex{5}\)). Each subunit is arranged as a linear …
Fibronectin at a glance | Journal of Cell Science | The Company of ...
2002年10月15日 · Fibronectin (FN) mediates a wide variety of cellular interactions with the extracellular matrix (ECM) and plays important roles in cell adhesion,migration, growth and …
Role of fibronectin in normal wound healing - PMC - PubMed …
Fibronectin plays many different roles in the wound healing process because of the presence of specific function domains and binding sites in its structure. Fibronectin interacts with different …
Plasma and cellular fibronectin: distinct and independent …
2011年9月16日 · Fibronectin (FN) is a ubiquitous extracellular matrix (ECM) glycoprotein that plays vital roles during tissue repair. The plasma form of FN circulates in the blood, and upon …
Fibronectin: Molecular Structure, Fibrillar Structure and ... - MDPI
2021年9月16日 · In times of ECM assembly and turnover, cells upregulate assembly of the ECM protein, fibronectin (FN). FN is assembled by cells into viscoelastic fibrils that can bind upward …
Fibronectins, Their Fibrillogenesis, and In Vivo Functions
Fibronectin (FN) is a multidomain protein with the ability to bind simultaneously to cell surface receptors, collagen, proteoglycans, and other FN molecules. Many of these domains and …
Fibronectin and Its Receptors in Hematopoiesis - PMC
2020年12月18日 · Fibronectin exerts a variety of functions by acting on cell surface receptors. It modulates proliferation, inhibits apoptosis, supports migration, and regulates differentiation [9, …