Diacerein: Uses, Interactions, Mechanism of Action - DrugBank …
2016年10月20日 · Diacerein is an slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis.
Diacerein - Wikipedia
The use of diacerein is to be limited to treating symptoms of osteoarthritis affecting the hip or knee. Diacerein should not be administered during pregnancy and lactation.
[Mechanisms of action of diacerein, the first inhibitor of …
2004年5月22日 · Two mechanisms of action have been validated: in vitro inhibition of interleukin-1 (IL-1) synthesis, the main cytokine involved in cartilage destruction, and activity on the …
Efficacy, residual effectiveness and safety of diacerein in the ...
We systematically reviewed the efficacy, safety, and residual effectiveness of diacerein. To estimate the symptomatic efficacy, residual effect and safety of diacerein in the treatment of …
An Update of Anthraquinone Derivatives Emodin, Diacerein, and …
While different clinical trials have been performed until now on diacerein and diabetes, our review only discusses two very recent meta-analyses that deeply analyzed the effects of diacerein in …
Diacerein - an overview | ScienceDirect Topics
Diacerein is a disease-modifying drug for the treatment of OA with interleukin (IL) 1 inhibitory properties.
Diacerein - an overview | ScienceDirect Topics
Diacerein, also known as diacetylrhein, is used in osteoarthritic conditions. Its mechanism involves inhibition of interleukin-1 beta without affecting prostaglandin biogenesis upon its …
Diacerein: Recent insight into pharmacological activities and …
2020年11月1日 · This review, the first of its kind, highlights the proposed roles of diacerein in osteoarthritis and discusses recent results supporting its emerging roles with a particular focus …
Diacerein | Drugs - Springer
2012年10月19日 · Diacerein had similar efficacy to NSAIDs, but a slower onset of action, in comparative trials of 2 months’ duration conducted in patients with osteoarthritis. The …
Diacerein | C19H12O8 | CID 26248 - PubChem
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects …