地喹氯铵 - 维基百科，自由的百科全书
地喹氯铵（英語： dequalinium chloride ），中国称氯化克菌定，是一种 bola型 （ 英语 ： bolaamphiphile ） 季铵盐，有消毒作用。 一般以氯化物形式存在，但也有其他卤素盐（例如地喹 碘 铵）存在。
Dequalinium chloride - DrugBank Online
Dequalinium chloride. Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. 9 It is a quaternary ammonium compound, 10 as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic ...
地喹氯铵 | 522-51-0 - ChemicalBook
Dequalinium Chloride (DECA)是一种阳离子亲脂性PKC抑制剂。当暴露在UV光下时，DECA共价结合并不可逆地抑制PKCα和PKCβ。 体内研究 在负荷膀胱MB49肿瘤的小鼠体内，Dequalinium chloride (2 mg/kg/d, i.p.)表现出抗癌活性，T/C 为210%。 用途
Dequalinium: Uses, Interactions, Mechanism of Action - DrugBank …
Jun 13, 2005 · Dequalinium is a quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat, as well as vaginal candidiasis.
Dilute 1 mL of the solution to 10 mL with methanol R. Reference solution (c). Dissolve 5 mg of tropine CRS in methanol R and dilute to 100.0 mL with the same solvent. Reference solution (d). Dissolve 10 mg of deptropine citrate CRS and 10 mg of tropine CRS in methanol R and dilute to 25 mL with the same solvent.
Dequalinium - Wikipedia
Dequalinium is a quaternary ammonium cation and bolaamphiphile commonly available as the dichloride salt. It is useful as an antiseptic and disinfectant. The bromide, iodide, acetate, and undecenoate salts are known as well. Dequalinium chloride is …
DEQUALINIUM CHLORIDE - National Center for Advancing …
Dequalinium Chloride (DECA) is a PKC inhibitor and high-affinity blocker CNGA1 channel, and nearly as effective on heteromeric CNGA1+CNGB1 channels. Common side effects are: vaginal discharge; vaginal itching or vaginal burning; vaginal yeast infection (thrush); tender tongue.
DEQUALINIUM - National Center for Advancing Translational …
Dequalinium Chloride (DECA) is a PKC inhibitor and high-affinity blocker CNGA1 channel, and nearly as effective on heteromeric CNGA1+CNGB1 channels. Common side effects are: vaginal discharge; vaginal itching or vaginal burning; vaginal yeast infection (thrush); tender tongue.
PATIENT & CAREGIVER EDUCATION. Dequalinium. This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. What is this drug used for? It is used to treat vaginal infections.
Medicinal applications and molecular targets of dequalinium chloride ...
For more than 60 years dequalinium chloride (DQ) has been used as anti-infective drug, mainly to treat local infections. It is a standard drug to treat bacterial vaginosis and an active ingredient of sore-throat lozenges.