Probe - National Human Genome Research Institute
2024年11月7日 · A probe is a single-stranded sequence of DNA or RNA used to search for its complementary sequence in a sample genome. The probe is placed into contact with the sample under conditions that allow the probe sequence to hybridize with its complementary sequence.
DNA Probes: Labeling, Types, Applications and Limitations
2019年12月20日 · DNA probes are single-stranded and labeled oligonucleotide sequences used in FISH, PCR and DNA sequencing. Learn about DNA probes, types, examples and various types of labeling techniques. Also, explore applications of DNA probes, in this article.”
DNA Probe - an overview | ScienceDirect Topics
DNA probes are single stranded (ss) or double stranded (ds), sequence specific DNA oligonucleotides (20–30 bp) designed to capture target oligonucleotides and may contain NEases recognition sites at defined positions.
DNA probes - Latest research and news - Nature
2024年6月10日 · DNA probes are stretches of single-stranded DNA used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization. DNA probes are usually labelled, for...
DNA Probes & DNA Hybridisation | AQA A Level Biology Revision …
2021年10月26日 · A DNA probe is a short length of single-stranded DNA that has a known base sequence complementary to the specific base sequence of a known allele. The probe is usually attached to a radioactive or fluorescent label that indicates its position.
Probe Design, Production, and Applications | SpringerLink
A probe is a nucleic acid molecule (single-stranded DNA or RNA) with a strong affinity with a specific target (DNA or RNA sequence). Probe and target base sequences must be complementary to each other, but depending on conditions, they do not necessarily have to be exactly complementary.
DNA nanostructure-based nucleic acid probes: construction and ...
DNA nanostructures can bind with nucleic acid probes, constructing biosensors that can detect various targets such as nucleic acids, metal ions, small molecules, proteins, and cells, as well as pH. To date, DNA nanostructure-based nucleic acid probes have been widely used in …
Isolating, Cloning, and Sequencing DNA - Molecular Biology of …
DNA probes are often used to detect, in a complex mixture of nucleic acids, only those molecules with sequences that are complementary to all or part of the probe.
Fluorescence In Situ Hybridization (FISH) - Nature
In molecular hybridization, a labeled DNA or RNA sequence is used as a probe to identify or quantify the naturally occurring counterpart of the sequence in a biological sample.
Nucleic Acid Probe - an overview | ScienceDirect Topics
Nucleic acid probes consist of DNA or RNA segments that bind to complementary sequences of DNA or RNA in a target organism. Once a probe hybridizes with its target sequence, it forms a stable double-stranded molecule with its target sequence. …
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