Colistin - Wikipedia
Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections including pneumonia. [7] [8] These may involve bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, or Acinetobacter. [9]
Colistin: Antibiotic Uses, Warnings, Side Effects, Dosage - MedicineNet
Colistin is an antibiotic used to treat acute and chronic bacterial infections from susceptible strains of certain gram-negative bacteria. Colistin is toxic to the kidneys. Discontinue therapy if there are signs of impaired kidney function.
Colistin: Uses, Interactions, Mechanism of Action - DrugBank Online
Colistin is a polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Colistin: Side Effects, Uses, Dosage, Interactions, Warnings
What Is Colistin Used For and How Does it Work? Colistin is used to treat certain bacterial infections. Colistin is available under the following different brand names: colistimethate sodium and Coly Mycin M. What Are Dosages of Colistin? Dosage Forms and Strengths. Powder for Injection. Dosage Considerations – Should be Given as Follows:
colistimethate sodium, Coly Mycin M (colistin) dosing, indications ...
Medscape - Indication-specific dosing for colistimethate sodium, Coly Mycin M (colistin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation...
Colistin (Colistimethate Sodium) Injection: Uses, Side Effects ... - WebMD
Colistimethate is an antibiotic used to treat certain bacterial infections. It works by stopping the growth of bacteria. Colistimethate for injection is usually given into a vein or a muscle...
Polymyxins: An overview - UpToDate
2022年11月22日 · Colistin was historically given as an intramuscular injection for the treatment of gram-negative bacterial infections, but fell out of favor after aminoglycosides became available because of its significant side effects, particularly nephrotoxicity.
Colistin Dosing Recommendations and Formulary Guidelines
Colistin is a polymyxin antibiotic administered as the prodrug colistimethate. Due to poor pharmacokinetics, administration of colistin intravenously is only recommended for urinary tract infections or as inhalation therapy for multi-drug resistant bacteria. 1 Polymyxin B is the preferred agent from this class for most systemic infections.
Colistin and its role in the Era of antibiotic resistance: an ... - PubMed
Colistin has re-emerged as a last-hope treatment in the mid-1990s against MDR Gram-negative pathogens due to the development of extensively drug-resistant GNB. Unfortunately, rapid global resistance towards colistin has emerged following its resurgence.
The History of Colistin Resistance Mechanisms in Bacteria: …
In this review, through the history of colistin, we underline the methods used over the last decades, both old and recent, to facilitate the discovery of the main colistin resistance mechanisms and how new technological approaches may help to improve the rapid and efficient exploration of new target genes.