Mechanisms of synovial joint and articular cartilage development …
2019年6月14日 · Cartilage anlagen grow to form a cartilage template, accompanied by chondrocyte proliferation and differentiation, which has a similar shape to future bones. At the center of the cartilage, chondrocytes undergo hypertrophic differentiation and then apoptosis, resulting in vascular invasion and ossification by osteoblasts.
Cartilage anlagen adapt in response to static deformation
2006年1月1日 · Connective tissue adaptation, including the development of cartilaginous anlagen into bones, is widely believed to be related to dynamic, intermittent load and stress histories. Static stresses, on the other hand, are generally believed deleterious in tissue adaptation.
Cartilage anlagen adapt in response to static deformation
Connective tissue adaptation, including the development of cartilaginous anlagen into bones, is widely believed to be related to dynamic, intermittent load and stress histories. Static stresses, on the other hand, are generally believed deleterious in tissue adaptation.
Introduction to Cartilage Tissue: Development, Structure, and …
2023年7月12日 · From the embryonic stage to skeletal maturity, cartilage tissue serves as a template for bone development, thereby before the onset of bone formation, the skeletal template in the early embryonic limb is made of a contiguous cartilaginous anlage with flattened, compressed, and homogenous mesenchymal cells which are named as “interzone” (as ...
Chondrogenesis, chondrocyte differentiation, and articular cartilage ...
During skeletal development, chondrocytes arise from mesenchymal progenitors to synthesize the templates, or cartilage anlagen, for the developing bone [Goldring et al. 2006]. Chondrogenesis occurs as a result of condensation of mesenchymal cells, which express collagens I, III and V, and chondroprogenitor cell differentiation with expression ...
Exploiting endogenous fibrocartilage stem cells to regenerate cartilage …
2016年10月10日 · Here we show resident fibrocartilage stem cells (FCSCs) can be used to regenerate and repair cartilage. We identify FCSCs residing within the superficial zone niche in the temporomandibular joint...
Articular cartilage and joint development from embryogenesis …
2017年2月1日 · This review focuses on recent advances in knowledge of embryonic and postnatal articular cartilage development, growth and morphogenesis, providing essential insight into not only the developmental biology of the articular cartilage, but also into potential biomedical strategies for repair.
Structure, formation and role of cartilage canals in the developing ...
2008年8月28日 · Most parts of the human skeleton develop out of initial cartilaginous anlagen, taking form via temporally and spatially well-coordinated perichondral (intramembranous) and endochondral ossification processes.
Bioengineering Cartilage Growth, Maturation, and Form
Cartilage of articular joints grows and matures to achieve characteristic sizes, forms, and functional properties. Through these processes, the tissue not only serves as a template for bone...
Changes in mechanics and composition of human talar cartilage anlagen ...
Objective: Fetal cartilage anlage provides a framework for endochondral ossification and organization into articular cartilage. We previously reported differences between mechanical properties of talar cartilage anlagen and adult articular cartilage.