Chemistry, Synthesis, and Structure Activity Relationship of ... - MDPI
2023年11月14日 · The reaction between o-phenylenediamine and benzil derivatives in the presence of hexafluoroisopropanol (HFIP) was run at room temperature for one hour to produce quinoxaline derivatives with a 95% yield.
Quinoxalines: Synthesis, Reactions, Mechanisms and Structure
The first and only book that comprehensively describes the opportunities quinoxalines offer as reagents for the synthesis of biologically important condensed derivatives. The book explains new acid-catalyzed rearrangements of quinoxalinones giving benzimidazoles when exposed to nucleophilic reactants, thus leading to biheterocyclic systems.
Novel Synthetic Routes to Prepare Biologically Active Quinoxalines …
This review paper highlights the various synthetic routes to prepare quinoxaline and its derivatives, covering the literature for the last two decades. A total of 31 schemes have been explained using the green chemistry approach, cost-effective methods, and quinoxaline derivatives’ therapeutic uses.
Quinoxaline: A comprehension of current pharmacological …
2022年8月1日 · Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several quinoxalines analogous displayed their distinct pharmacological activities.
Novel Synthetic Routes to Prepare Biologically Active ... - MDPI
2021年2月18日 · This review paper highlights the various synthetic routes to prepare quinoxaline and its derivatives, covering the literature for the last two decades. A total of 31 schemes have been explained using the green chemistry approach, cost-effective methods, and quinoxaline derivatives’ therapeutic uses. Keywords:
Recent advances in the synthesis and reactivity of quinoxaline
The last few decades have witnessed several publications utilizing quinoxaline scaffolds for the design and development of numerous bioactive molecules, dyes, fluorescent materials, electroluminescent materials and organic sensitizers for solar cell applications and polymeric optoelectronic materials.
Recent advances in the transition-metal-free synthesis of …
2021年11月11日 · Quinoxalines, also known as benzo [a]pyrazines, constitute an important class of nitrogen-containing heterocyclic compounds as a result of their widespread prevalence in natural products, biologically active synthetic drug candidates, and optoelectronic materials.
Quinoxaline - Wikipedia
A quinoxaline, also called a benzopyrazine, in organic chemistry, is a heterocyclic compound containing a ring complex made up of a benzene ring and a pyrazine ring. It is isomeric with other naphthyridines including quinazoline, phthalazine and cinnoline. [3] It is a colorless oil that melts just above room temperature.
Multicomponent and One-pot Syntheses of Quinoxalines
2020年12月31日 · Perlite-SO 3 H nanoparticles acting as a catalyst for the three-component synthesis of N-cyclohexyl-3-aryl-quinoxaline-2-amine derivatives can be easily prepared. The quinoxaline synthesis starts from 1,2-diaminoarenes, aromatic aldehydes and cyclohexyl isocyanide under ultrasonication and gives nine quinoxaline derivatives in excellent yields.
Asian Journal of Organic Chemistry
2021年12月23日 · This review segregates and outlines all the aspects of the synthesis of Benzil for almost two centuries. Here, state of the art review includes the early synthesis in 1836 to the advancement made over the past years in the knowledge of the preparation of …