Atomoxetine - StatPearls - NCBI Bookshelf - National Center for ...
2023年3月27日 · This activity outlines the indications, mechanism of action, administration, adverse effects, contraindications, and monitoring of atomoxetine. Atomoxetine is indicated for treating attention deficit hyperactivity disorder (ADHD) in adults and children over six years.
Atomoxetine - Wikipedia
Atomoxetine, sold under the brand name Strattera, is a selective norepinephrine reuptake inhibitor medication used to treat attention deficit hyperactivity disorder (ADHD) [12] and, to a lesser extent, cognitive disengagement syndrome.
Atomoxetine: Uses, Interactions, Mechanism of Action
Mechanism of action Atomoxetine is known to be a potent and selective inhibitor of the norepinephrine transporter (NET), 2 which prevents cellular reuptake of norepinephrine throughout the brain, which is thought to improve the symptoms of ADHD.
Frontiers | The Mechanism, Clinical Efficacy, Safety, and Dosage ...
2022年2月8日 · Mechanism of Action. While the precise mechanism of action (MOA) through which atomoxetine produces its therapeutic effects is unclear, the putative hypotheses have been elucidated (28, 31). Atomoxetine is thought to be related to its selective inhibition of presynaptic NE reuptake in the PFC .
Atomoxetine: a review of its use in attention-deficit hyperactivity ...
The mechanism of action of atomoxetine is unclear, but is thought to be related to its selective inhibition of presynaptic norepinephrine reuptake in the prefrontal cortex. Atomoxetine has a high affinity and selectivity for norepinephrine transporters, but little or no affinity for various neurotransmitter receptors.
AtoMOXetine: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月9日 · Mechanism of Action. Selectively inhibits the reuptake of norepinephrine (Ki 4.5 nM) with little to no activity at the other neuronal reuptake pumps or receptor sites. Pharmacokinetics/Pharmacodynamics Absorption. Rapid. Distribution. V d: …
Perspectives in Psychopharmacology: Spotlight on Atomoxetine
Unlike methylphenidate and dextroamphetamine, which act primarily by blocking the reuptake of dopamine, atomoxetine selectively inhibits the presynaptic reuptake of norepinephrine (Banaschewski T, et al., 2004). It has been approved for use and indicated in children (6 years of age and older), adolescents, and adults with ADHD.
The Mechanism, Clinical Efficacy, Safety, and Dosage Regimen of ...
2022年2月9日 · Atomoxetine inhibits the presynaptic norepinephrine transporter (NET), preventing the reuptake of NE throughout the brain along with inhibiting the reuptake of dopamine in specific brain regions such as the prefrontal cortex (PFC).
2020年9月10日 · Medications approved by the Food and Drug Administration (FDA) comprise stimulants (amphetamines and methylphenidate) and nonstimulants (atomoxetine and extended-release clonidine and guanfacine...
Atomoxetine - PubMed
2023年3月27日 · Although atomoxetine is only FDA-approved for treating ADHD, it is sometimes used off-label to treat adult patients with treatment-resistant depression. This activity outlines the indications, mechanism of action, administration, adverse effects, contraindications, and monitoring of atomoxetine.