Glycerol 3-phosphate - Wikipedia
From a historical reason, it is also known as L-glycerol 3-phosphate, D-glycerol 1-phosphate, L-α-glycerophosphoric acid. Glycerol 3-phosphate is synthesized by reducing dihydroxyacetone phosphate (DHAP), an intermediate in glycolysis. The reduction is catalyzed by glycerol-3-phosphate dehydrogenase.
Glycerol phosphate shuttle - Wikipedia
The glycerol-3-phosphate shuttle is a mechanism used in skeletal muscle and the brain [1] that regenerates NAD + from NADH, a by-product of glycolysis. NADH is a reducing equivalent that stores electrons generated in the cytoplasm during glycolysis. NADH must be transported into the mitochondria to enter the oxidative phosphorylation pathway.
The function and the role of the mitochondrial glycerol-3 …
2013年3月1日 · In this review we summarize the present knowledge on the structure and regulation of mGPDH and discuss its metabolic functions, reactive oxygen species production and tissue and organ specific roles in mammalian mitochondria …
Glycerophosphate - an overview | ScienceDirect Topics
Glycerophosphate is an organic compound naturally found in the body which is usually used as a source of phosphate in the treatment of unbalance of phosphate metabolism. In this review, the recent advances in the development of chitosan thermosensitive hydrogels based on different glycerophosphate are summarized including preparation ...
Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and …
2024年5月1日 · In this review, we combined several critical studies on the roles of the GPS proteins GPD1 and GPD2 to summarize the current understanding of the metabolic and functional impacts of GPS,...
Glycerophosphoric acid | C3H9O6P | CID 754 - PubChem
Glycerol 1-phosphate is a glycerol monophosphate having the phosphate group located at position 1. It has a role as a human metabolite and an algal metabolite. It is a conjugate acid of a glycerol 1-phosphate (2-). Glycerol 3-phosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
alpha-Glycerophosphate shuttle in a clonal beta-cell line
It has been proposed that the alpha-glycerophosphate (alpha-GOP) shuttle plays a crucial role in regulation of glycolysis in beta-cells by linking reoxidation of cytosolic NADH to formation of ATP in the electron transport chain (J. Biol. Chem. 265: …
Glycerophosphate | Sigma-Aldrich - MilliporeSigma
Find glycerophosphate and related products for scientific research at MilliporeSigma
Glycerophosphates - SpringerLink
2016年1月1日 · Glycerophosphate is an important substrate for the synthesis of diacylglycerols, triacylglycerols, and glycerophospholipids. Additionally to its role as intermediate in biosynthesis of lipids, GPA has various functions in lipid signaling and membrane dynamics.
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage
2019年8月5日 · Here we find that in macrophages activated by bacterial lipopolysaccharide (LPS), mitochondrial glycerol 3-phosphate dehydrogenase (GPD2) regulates glucose oxidation to drive inflammatory responses.