Thyrotropin-releasing hormone - Wikipedia
Thyrotropin-releasing hormone (TRH) is a hypophysiotropic hormone produced by neurons in the hypothalamus that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin from the anterior pituitary.
Thyroid Hormone: What It Is & Function - Cleveland Clinic
2022年2月15日 · Thyroid hormone is the hormone that controls your body’s metabolism, the process in which your body transforms the food you eat into energy. The two main hormones your thyroid releases — thyroxine (T4) and triiodothyronine (T3) — …
Thyrotropin-releasing hormone | Hormones
Thyrotropin-releasing hormone is the master regulator of thyroid gland growth and function (including the secretion of the thyroid hormones thyroxine and triiodothyronine). These hormones control the body’s metabolic rate, heat generation, neuromuscular function and …
Physiology, Thyroid Hormone - StatPearls - NCBI Bookshelf
2023年6月5日 · Hypothalamus releases thyrotropin-releasing hormone (TRH) that stimulates the secretion of TSH in the pituitary gland. Increased free T4 and T3 inhibit the release of TRH and TSH through a negative feedback loop. As a result, …
Thyrotropin-releasing hormone | TRH, Hypothalamus, Pituitary
thyrotropin-releasing hormone, simplest of the hypothalamic neurohormones, consisting of three amino acids in the sequence glutamic acid–histidine–proline. The structural simplicity of thyrotropin-releasing hormone is deceiving because this hormone actually has many functions.
Regulation of the Hypothalamic Thyrotropin Releasing Hormone (TRH ...
Thyrotropin-releasing hormone (TRH) produced in the parvocellular division of the hypothalamus is the key peptide hormone responsible for HPT regulation. TRH is synthesized from a larger inactive precursor (proTRH) by a series of post-translational modifications while transported through the regulated secretory pathway (RSP).
New Insights into Thyroid Hormone Action - PMC - PubMed …
Thyroid hormones (TH) are endocrine messengers essential for normal development and function of virtually every vertebrate. The hypothalamic-pituitary-thyroid axis is exquisitely modulated to maintain nearly constant TH (T4 and T3) concentrations in circulation.
Physiology, Thyroid Stimulating Hormone - StatPearls - NCBI Bookshelf
2023年5月1日 · Thyroid-stimulating hormone, also known as TSH, is a glycoprotein hormone produced by the anterior pituitary. It is the primary stimulus for thyroid hormone production by the thyroid gland. It also exerts growth effects on thyroid follicular cells leading to …
Thyrotropin-releasing Hormone - Thyroid UK
2021年10月18日 · Thyrotropin-releasing hormone (TRH) is a hormone produced by the hypothalamus which plays an important role in the regulation of thyroid gland activity. 1 What does thyrotropin-releasing hormone do? Made up of just three amino acid components, its main purpose is to stimulate the release of thyrotropin also known as thyroid-stimulating hormone ...
Thyroid Hormone Regulation of Metabolism - PMC - PubMed …
The thyroid hormone receptor (TR) isoforms, α and β, are differentially expressed in tissues and have distinct roles in TH signaling. Local activation of thyroxine (T 4), to the active form, triiodothyronine (T 3), by 5′-deiodinase type 2 (D2) is a key mechanism of TH regulation of …