New Insights into the Role of PPARγ in Skin Physiopathology
2024年6月19日 · In addition to its relevance in SG morphogenesis, PPARγ also plays a key role in the maintenance of the SG primary function, namely sebum production, since its expression …
Peroxisome proliferator-activated receptors (PPARs) in skin …
2007年8月1日 · PPARβ/δ regulates sebocyte differentiation, promotes hair follicle growth and has pro-differentiating effects in keratinocytes in normal and inflammatory conditions. In contrast, …
Peroxisome Proliferator-Activated Receptors Increase Human Sebum ...
2006年9月1日 · Studies in sebocytes and human sebaceous glands indicate that agonists of peroxisome proliferator-activated receptors (PPARs) alter sebaceous lipid production. The …
New Insights into the Role of PPARγ in Skin Physiopathology
In addition to its relevance in SG morphogenesis, PPARγ also plays a key role in the maintenance of the SG primary function, namely sebum production, since its expression is associated with …
Peroxisome Proliferator-Activated Receptors (PPARs) and the …
2012年9月10日 · It has been proposed that PPARγ and PPARβ/δ antagonists might be used in the therapy of acne vulgaris to interfere selectively with sebum formation without producing …
Peroxisome proliferator-activated receptor γ (PPARγ): A master ...
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-modulated transcription factor that governs the expression of genes involved in inflammation, redox …
Peroxisome proliferator-activated receptors (PPARs) and PPAR
Trivedi et al. demonstrated that while isotretinoin reduced lipogenesis, PPARα, PPARγ PPARβ/δ, and PPAR pan agonist induced sebum production was significantly higher in patients with …
(PDF) Peroxisome Proliferator-Activated Receptors Increase Human Sebum ...
2006年10月1日 · Studies in sebocytes and human sebaceous glands indicate that agonists of peroxisome proliferator-activated receptors (PPARs) alter sebaceous lipid production. The …
PPARγ phase separates with RXRα at PPREs to regulate target …
2022年4月26日 · Peroxisome proliferator-activated receptor (PPAR)-γ is a key transcription activator controlling adipogenesis and lipid metabolism. PPARγ binds PPAR response …
The role of PPARγ‐mediated signalling in skin biology and …
2015年2月3日 · Activated PPARs heterodimerize with the retinoid X receptor (RXR) in the presence of activators and bind to a PPAR response element (PPRE) in the promoters of …