Memory T cell - Wikipedia
Lifetime overview. Memory T cells undergo different changes and play different roles in different life stages for humans. At birth and early childhood, T cells in the peripheral blood are mainly naïve T cells. [10] Through frequent antigen exposure, the population of memory T …
Memory T Cell - an overview | ScienceDirect Topics
Memory T cells are antigen-specific T cells that remain long-term after an infection has been eliminated. The memory T cells are quickly converted into large numbers of effector T cells upon reexposure to the specific invading antigen, thus providing a rapid response to past infection.
Memory T-Cell Heterogeneity and Terminology - PMC
Here, we review our current knowledge of differentiation and maintenance of memory and exhausted CD8 T cells, including phenotypic classification, developmental paths, transcriptional and epigenetic features, and cell intrinsic and extrinsic factors.
Human memory T cells: generation, compartmentalization and
2013年12月13日 · Memory T cells constitute the most abundant lymphocyte population in the body for the majority of a person's lifetime; however, our understanding of memory T cell generation, function...
Two parallel worlds of memory T cells | Nature Immunology
2020年10月28日 · In contrast with the classical dogma that the pathways generating either memory or ‘exhausted’ T cells are strictly segregated, data now identify a clonally distinct hybrid memory T cell...
Immunological memory cells - PMC
This article reviews immunological memory cells, currently represented by T and B lymphocytes and natural killer (NK) cells, which determine a rapid and effective response against a second encounter with the same antigen. Among T lymphocytes, ...
T cell responses: naïve to memory and everything in between
T cell memory. T cells may assume many phenotypes in response to stimulation. The eventual fate of a T cell depends on many environmental queues, including, but not limited to, cytokines, inflammatory and immune-modulatory products, and tissue-specific factors.
The origins of memory T cells - Nature
2017年12月13日 · Memory T cells protect against previously encountered pathogens, but their origins are unclear. Two studies track DNA modifications over time and find that these cells arise from effector...
Memory T Cell - an overview | ScienceDirect Topics
Following an immune response, small numbers of T cells persist long term and are called memory T cells. Memory T cells function to protect the host from reinfection by the same micro-organisms and protection correlates with the number of specific memory cells present in the host.
Human memory T cells: generation, compartmentalization and …
In this Review, we discuss studies focused on human memory T cells that reveal key properties of these cells, including subset heterogeneity and diverse tissue residence in multiple mucosal and lymphoid tissue sites.
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