Lactam - Wikipedia
A lactam is a cyclic amide, formally derived from an amino alkanoic acid through cyclization reactions. The term is a portmanteau of the words lactone + amide. Greek prefixes in …
β-Lactams: chemical structure, mode of action and ... - LWW
2012年6月20日 · β-Lactams are a group of antibiotics that have specificity for bacteria. Bacteria are prokaryotic and, hence, offer numerous structural and metabolic effects that differ from …
Structural Insights for β-Lactam Antibiotics - PMC
In this review, we attempt to interpret the structural features of β-lactams to mimic the D-Ala-D-Ala dipeptide as the target structure and inhibit peptidoglycan synthesis in bacterial cell walls. In …
Lactam - Synthesis, Structure, Types of Lactam and Uses of ...
What is Lactam? A lactam is a cyclic amide, which is derived from an amino alkanoic acid. The term is a portmanteau of the words acetone + amide. Lactams form by the acid-catalysed …
Lactam | C14H17NO3 | CID 53982816 - PubChem
Lactam | C14H17NO3 | CID 53982816 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity …
β-Lactam - Wikipedia
A lactam is a cyclic amide, and beta-lactams are named so because the nitrogen atom is attached to the β-carbon atom relative to the carbonyl. The simplest β-lactam possible is 2-azetidinone. …
β-Lactamases: Sequence, Structure, Function, and Inhibition
β-Lactams were the first class of antibiotics to be discovered and the second to be introduced into the clinic in the 1940s [1]. They inhibit bacterial transpeptidases (also known as penicillin …