Immunohistochemistry - Wikipedia
Immunohistochemistry is a form of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells and tissue, by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
Immunohistochemistry: What Is It and How Does It Work? - Healthline
2023年4月3日 · Immunohistochemistry (IHC) is a widely used staining technique that allows doctors to detect certain cancers and infectious diseases more easily. Since its introduction in 1941, scientists have...
【实验技术学习笔记】免疫组织化学染色法（IHC） - 知乎
免疫组织化学（Immunohistochemistry，IHC）是利用抗原与抗体特异性结合的原理，通过化学反应使标记抗体的显色剂（荧光素、酶、金属离子、同位素）显色来确定组织细胞内抗原（多肽和蛋白质）。 即带显色剂标记的特异性抗体在组织细胞与对应组织结合化学反应显色，对其进行定位、定性及定量的研究： 它把免疫反应的特异性、组织化学的可见性巧妙地结合起来，借助显微镜（包括荧光显微镜、电子显微镜）的显像和放大作用，在细胞、亚细胞水平检测各种抗原物质（如 …
What Is Immunohistochemistry? - Cleveland Clinic
Immunohistochemistry (IHC) uses antibodies to detect antigens in a tissue sample. It’s one lab technique a pathologist may use to check for signs of disease following a biopsy. IHC is commonly used to diagnose cancer, predict treatment response and determine likely outcomes (prognosis) of the disease. What is immunohistochemistry (IHC)?
免疫組織化學 - 维基百科，自由的百科全书
免疫組織化學染色（immunohistochemical staining）属一种免疫染色（immunostaining），是在抗體上結合螢光或可呈色的化學物質，利用此经修饰后的抗体与生物组织中的抗原具特异性结合的免疫學原理，选择性地识别组织切片或涂片细胞中的抗原，檢測細胞或組織中是否 ...
免疫组织化学 (IHC) - Cell Signaling Technology (CST)
免疫组织化学（或 IHC）是一种基于抗体的技术，用于检测结构和组织已保留的组织中的蛋白表达。 Coons 等人于 1942 首次报告了 IHC 的使用，他们报告了开发荧光连接抗体来观察肺炎球菌。 它广泛用于医学研究实验室以及临床环境中，以研究生物样品中是否存在抗原。 这种技术依赖于一种抗体对某种表位的特异性检测。 通常，这种特殊的结合关系需要进行一些 优化 才能获得准确结果。 组织处理途径的多个方面可能会影响抗体与组织相互作用的方式，且应仔细调整以实现 …
An Introduction to the Performance of Immunohistochemistry
Immunohistochemistry (IHC) is a widely used ancillary testing method in anatomic surgical pathology for cell classification and diagnosis and utilizes antibodies targeted against certain antigens in specific tissues and cells to facilitate determination of cell type and organ of origin.
Immunohistochemistry: IHC Test for Cancer
2022年9月25日 · Immunohistochemistry (IHC) is a diagnostic technique conducted in a laboratory. It involves performing special tests on the patient's biopsy tissue sample to help diagnose disease more precisely. IHC helps the care team distinguish between different types and subtypes of a disease by identifying specific molecules within cells, known as markers.
Overview of Immunohistochemistry | Thermo Fisher Scientific
Immunohistochemistry (IHC) combines anatomical, immunological and biochemical techniques to image discrete components in tissues by using appropriately-labeled antibodies to bind specifically to their target antigens in situ.
Principles and methods of immunohistochemistry - PubMed
Immunohistochemical techniques detect antigens in tissue sections by means of immunological and chemical reactions. This technique is highly sensitive and specific and can detect a wide variety of antigens in multiple animal species. This chapter reviews common immunohistochemical methods used in th …