Growth hormone - Wikipedia
Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals.
Physiology, Growth Hormone - StatPearls - NCBI Bookshelf
2023年5月1日 · Human growth hormone (HGH), also known as somatotropin, is a 191 amino acid single-chain polypeptide produced by somatotropic cells within the anterior pituitary gland. As its name implies, scientists originally found it to be responsible for …
Molecule of the Month: Growth Hormone - RCSB: PDB-101
Growth hormone is one key growth signal released from the pituitary, a pea-sized gland located at the base of the brain. Lack of this hormone in children can cause them to remain shorter than average, while in its excess they may grow taller than most.
Growth hormone — past, present and future | Nature Reviews …
2018年3月16日 · In this Review, the authors chart the history of growth hormone, from discovery to clinical development and therapeutic approval, and discuss the emerging pathophysiology and treatment of its...
Growth hormone | C78H110N22O30S6 | CID 170907453 - PubChem
A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.
Growth hormone: isoforms, clinical aspects and assays interference
GH is a polypeptide hormone exhibiting molecular heterogeneity. It consists of a complex mixture of molecular isoforms and their multimers. In humans, the genetic locus that codes GH resides on chromosome 17q24.2 [4, 5], has 46.83 kilobases and contains five GH related genes. These multiple genes most likely arose from gene duplication.
Growth Hormone - SpringerLink
2009年1月1日 · Human growth hormone (hGH) is a proteohormone secreted by the pituitary gland. It acts through binding to the hGH receptor, inducing either direct effects or initiating the production of insulin-like growth-factor I (IGF-I), the most important mediator of hGH effects.
Growth hormone, human | C72H132 | CID 168009821 - PubChem
2021年10月14日 · Somatotropin, or growth hormone, stimulates mitosis, cell growth, and, for some cell types, differentiation in many tissues of the body. It has profound effects on many aspects of gene expression and metabolism.
Growth Hormone Gene Family and Its Evolution | IntechOpen
2023年3月6日 · In this review, we will analyze the family of growth hormone (GH) genes, the territories where they are produced, the proteolytic generation of GH isoforms, both at the pituitary and tissue levels, the biological activity of these molecular forms, and we will describe the new variant GH-V2 and its effects biological.
Growth Hormone - an overview | ScienceDirect Topics
Growth hormone (GH) is a single-chain protein of 191 amino acids with a molecular size of approximately 22 kDa that is synthesized by and secreted from the somatotroph cells of the anterior pituitary gland. GH exerts a broad spectrum of effects, leading to the promotion of growth and the regulation of carbohydrate, lipid, protein, and mineral ...