Somitogenesis - Embryology
5 天之前 · In humans, the first somite pair appears at day 20 and adds caudally at 1 somite pair/90 minutes until on average 44 pairs eventually form. A somite is added either side of the …
Nature背靠背 | 里程碑！体外揭示人类体节发生过程中“分节时钟” …
2020年1月8日，美国哈佛医学院的 Olivier Pourquié 教授研究团队在 Nature 上在线发表题为 In vitro characterization of the human segmentation clock 的文章， 利用体外培养的人源PSM细 …
The single-cell transcriptional landscape of mammalian ... - Nature
2019年2月20日 · At the early-somite stages, the embryo transits from gastrulation to early organogenesis, forming the neural plate and heart tube (E8.0–E8.5). In the ensuing days …
Periodic formation of epithelial somites from human ... - Nature
2022年4月28日 · During embryonic development, epithelial cell blocks called somites are periodically formed according to the segmentation clock, becoming the foundation for the …
Somites: Formation and Role in Developing the Body Plan
2010年10月20日 · Somites are precursor populations of cells that give rise to important structures associated with the vertebrate body plan and will eventually differentiate into dermis, skeletal …
Cellular and molecular control of vertebrate somitogenesis
2024年2月28日 · Segmentation is a fundamental feature of the vertebrate body plan. This metameric organization is first implemented by somitogenesis in the early embryo, when …
Diverse Routes toward Early Somites in the Mouse Embryo
2021年1月11日 · Here, we describe three transcriptional trajectories toward somite formation in the early mouse embryo. Precursors of the anterior-most somites ingress through the primitive …
Paraxial mesoderm organoids model development of human …
2022年1月28日 · Paraxial mesoderm (PM) development involves the formation of embryonic segments called somites, which are produced sequentially from the presomitic mesoderm …
Diverse Routes toward Early Somites in the Mouse Embryo
Somite formation is foundational to creating the vertebrate segmental body plan. Here, we describe three transcriptional trajectories toward somite formation in the early mouse embryo. …
Somite Development: Constructing the Vertebrate Body - Cell Press
1998年1月9日 · Somites were first defined at the beginning of the last century, and much of our understanding of somite development comes from morphological observations and …