A Guide to Dendritic Cell Markers - Biocompare
2021年3月4日 · A Guide to Dendritic Cell Markers. Dendritic cells (DC) are bone marrow-derived immune cells that can be found in the blood, lymphoid organs, and various tissues in the body. They are generally stellate in morphology, with branching …
Dendritic Cells & their Markers - Bio-Rad
The table below lists key markers that can be used in the identification of DCs alongside the absence of lineage markers, such as CD3 (T cell), CD14 (monocyte), CD19 (B cell), CD56 (NK cell) and CD66b (granulocyte).
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells …
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, ...
Human dendritic cell subsets - PMC - PubMed Central (PMC)
Recent comparative phenotypic and functional studies have delineated a small number of distinct DC subsets that are widely distributed in all mammals (Table 1). In humans, all DCs express high levels of MHC class II (HLA-DR) and lack typical lineage markers CD3 (T cell), CD19/20 (B cell) and CD56 (natural killer cell).
Dendritic cell markers - Abcam
2024年4月23日 · Your guide to identifying and studying dendritic cell markers. Dendritic cells process antigen material and present on the cell surface to T cells. They originate from the bone marrow and migrate to various tissues. They are involved …
Dendritic Cell Overview | Thermo Fisher Scientific - US
Dendritic cells (DCs) play a pivotal role in the innate detection of pathogens and the subsequent activation of the adaptive immune response. DCs initiate the adaptive response by presenting antigenic peptides on major histocompatibility complex (MHC) molecules to induce T cell activation and differentiation.
Human dendritic cell subsets: an update - PMC - PubMed Central …
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid haematopoiesis that form an essential interface between the innate sensing of pathogens and the activation of adaptive immunity.
Comprehensive Phenotyping of Human Dendritic Cells and …
2020年11月16日 · Overview of traditional and recently described markers for human dendritic cells and monocytes. Peripheral blood mononuclear cells from four donors were analyzed with a 23-color flow cytometry panel (Table 2) containing conventional and recently suggested markers to delineate DC and monocyte subsets.
Dendritic cells as orchestrators of anticancer immunity and ...
2024年2月7日 · Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells that regulate adaptive immunity, including against cancer. Therefore, understanding the precise...
Expanding dendritic cell nomenclature in the single-cell era
2022年1月13日 · Here, we discuss the importance of differentiating cell subsets from cell states when annotating DC clusters and propose a revised nomenclature of the DC lineage that integrates experimentally ...