Chiral resolution - Wikipedia
Chiral resolution, or enantiomeric resolution, [1] is a process in stereochemistry for the separation of racemic mixture into their enantiomers. [2] It is an important tool in the production of optically active compounds, including drugs. [3] Another term with the same meaning is optical resolution.
Strategies for chiral separation: from racemate to enantiomer
2023年9月27日 · This review comprehensively summaries the latest developments in the main enantioseparation methods, including preparative-scale chromatography, enantioselective liquid–liquid extraction, crystallization-based methods for chiral separation, deracemization process coupling racemization and crystallization, porous material method and membrane ...
14.3: Chiral Chromatography - Chemistry LibreTexts
2020年8月20日 · The separation of enantiomers of chiral compounds by chromatographic methods and related techniques is one of the most important tasks in modern analytical chemistry, especially in the analysis of compounds of biological and pharmaceutical interest.
An overview of chiral separations of pharmaceutically active ...
This review provides a brief survey of chiral separation of pharmaceutically active substances published over the last 3 years (2018–2020). Chiral separation of drugs is an important area of research. The control of enantiomeric purity and ...
Advances in membrane-based chiral separation - ScienceDirect
2023年11月15日 · This review provides a systematic overview of the development of chiral separation membranes recently, involving the separation mechanism and membranes in liquid and solid forms. Meanwhile, the perspective of membranes for chiral separation is discussed.
Chiral Separations: A Review of Current Topics and Trends
2011年11月8日 · Are Highly Stable Covalent Organic Frameworks the Key to Universal Chiral Stationary Phases for Liquid and Gas Chromatographic Separations?. Journal of the American Chemical Society 2022 , 144 (2) , 891-900.
Strategies for chiral separation: from racemate to enantiomer
Chiral separation has become a crucial topic for effectively utilizing superfluous racemates synthesized by chemical means and satisfying the growing requirements for producing enantiopure chiral compounds.