Cell-Mediated Lysis - SpringerLink
Cell-mediated lysis describes the killing of specific cellular targets by cells of the immune system. The effector cells are most often differentiated CD8+ T cells (that is, cytotoxic T lymphocytes …
Immune Defenses - Medical Microbiology - NCBI Bookshelf
Local infections at surfaces such as the mucosa can elicit local cell-mediated and humoral (IgA) immune responses, but not necessarily systemic immunity. The host has multiple immune …
From periphery to center stage: 50 years of advancements ... - Cell …
Apr 25, 2024 · In adaptive immunity, the immune system responds to the invading pathogen by allowing clones of lymphocytes called B and T cells to expand, such that there are more of …
An introduction to immunology and immunopathology - PMC
Numerous cells are involved in the innate immune response such as phagocytes (macrophages and neutrophils), dendritic cells, mast cells, basophils, eosinophils, natural killer (NK) cells and …
The complement system and innate immunity
There are three ways in which the complement system protects against infection. First, it generates large numbers of activated complement proteins that bind covalently to pathogens, …
Innate immune sensing of cell death in disease and therapeutics
Sep 2, 2024 · Upon sensing pathogens, pathogen-associated molecular patterns or damage-associated molecular patterns, the innate immune system activates lytic, inflammatory cell …
From bacterial killing to immune modulation: Recent insights
Sep 21, 2017 · In addition to its direct antimicrobial role, more recent evidence has shown that lysozyme modulates the host immune response to infection. The degradation and lysis of …
Bacterial single-cell RNA sequencing captures biofilm …
3 days ago · It has been applied to assess immune response dynamics during bacterial infection, including biofilm, identifying transcriptional changes in leukocyte metabolism, reactive oxygen …
Phage lysis‐lysogeny switches and programmed cell death: Danse …
Nov 12, 2020 · Each temperate phage harbors a genetic locus that governs the “decision” between lysing the host cell or integrating in the genome, known as the lysis-lysogeny switch. …
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses …
6 days ago · Fig. 1: CD4 + T cell responses to vaccination with self- and foreign antigens partially depend on MHC-II epitope set occupancy. Fig. 4: Blockade of PD-1 and CD73 significantly …