Hydroxy ketone - Wikipedia
Alpha- and beta-hydroxy ketones. In organic chemistry, a hydroxy ketone (often referred to simply as a ketol) is a functional group consisting of a ketone (>C=O) flanked by a hydroxyl group (−OH). Chemicals in this group can be classified by the position of the hydroxyl relative to the ketone.
Beta-Hydroxy Ketone - an overview | ScienceDirect Topics
A Beta-Hydroxy Ketone is a compound that contains a ketone group and a hydroxyl group on the beta carbon atom. AI generated definition based on: Tetrahedron, 2004
β-Hydroxybutyrate: A Signaling Metabolite - PMC - PubMed …
Here, we review the signaling activities of the endogenous metabolite β-hydroxybutyrate (BHB). BHB is the most abundant ketone body in mammals. Ketone bodies are small molecules synthesized primarily in the liver from fats that circulate through the bloodstream during fasting, prolonged exercise, and when carbohydrates are restricted.
23.8: The Aldol Reaction and Condensation of Ketones and …
The fundamental transformation in this reaction is a dimerization of an aldehyde (or ketone) to a beta-hydroxy aldehyde (or ketone) by alpha C–H addition of one reactant molecule to the carbonyl group of a second reactant molecule.
23.1: Carbonyl Condensations - The Aldol Reaction
The aldol reaction takes advantage of a carbonyl compound’s ability to undergo both alpha substitution and nucleophilic addition reactions. The fundamental transformation in the aldol reaction is a dimerization of an aldehyde (or ketone) to form a beta-hydroxy aldehyde (or ketone).
β-Hydroxy ketone synthesis by addition - Organic Chemistry Portal
Treatment of vinyl ketones with a combination of TiCl 4 and n-Bu 4 NI followed by an addition of a variety of aldehydes provides syn-α-iodomethyl-β-hydroxy ketones with high stereoselectivity.
13.3: An Aldol Addition Forms β-Hydroxaldehydes or β …
2020年10月20日 · The fundamental transformation in this reaction is a dimerization of an aldehyde (or ketone) to a beta-hydroxy aldehyde (or ketone) by alpha C–H addition of one reactant molecule to the carbonyl group of a second reactant molecule.
20.6 Aldol reaction | Organic Chemistry II - Lumen Learning
In its usual form, it involves the nucleophilic addition of a ketone enolate to an aldehyde to form a β-hydroxy ketone, or “aldol” (aldehyde + alcohol), a structural unit found in many naturally occurring molecules and pharmaceuticals.
Aldol Addition and Condensation Reactions - Master Organic …
2022年4月14日 · When certain aldehydes are treated with strong base, two molar equivalents of the starting aldehyde may form a new C–C bond. The resulting product, a “beta-hydroxy aldehyde” contains both an ald ehyde and an alcoh ol. In addition to the new C–C bond, a C-H bond has broken, as has a C–O (pi) bond:
Hydroxy ketone synthesis by oxidation - Organic Chemistry Portal
A new and efficient chiral catalyst system, lanthanum-chiral BINOL-tris(4-fluorophenyl)phosphine oxide-cumene hydroperoxide, was developed for the epoxidation of α,β-unsaturated ketones, thus providing the corresponding epoxy ketones with excellent enantioselectivities (up to >99% ee) in good to excellent yields at room temperature.