Alprazolam: Uses, Interactions, Mechanism of Action - DrugBank
Indication. Alprazolam is indicated for the acute treatment of generalized anxiety disorder in adults. 18 Alprazolam is also indicated, either as a standard or extended-release formulation, for the treatment of panic disorder with or without agoraphobia in adults. 18, 19.
Alprazolam - Wikipedia
Alprazolam, sold under the brand name Xanax and others, is a fast-acting, potent tranquilizer of moderate duration within the triazolobenzodiazepine group of chemicals called benzodiazepines. [15] . Alprazolam is most commonly prescribed in the management of anxiety disorders, especially panic disorder and generalized anxiety disorder (GAD). [9] .
Alprazolam - StatPearls - NCBI Bookshelf
2023年4月24日 · Alprazolam, known by various trade names, is the most commonly prescribed psychotropic medication in the United States. Alprazolam is frequently prescribed to manage panic and anxiety disorders. Alprazolam has also been subject to misuse for recreational purposes because of its disinhibition, euphoria, and anxiolytic effects.
Demystifying Benzodiazepine Urine Drug Screen Results
2024年10月30日 · Alprazolam is metabolized after administration to the primary urinary metabolite alpha-hydroxyalprazolam. Thus, the presence of alprazolam and/or alpha-hydroxyalprazolam on a UDS would indicate recent alprazolam use. After administration, lorazepam undergoes glucuronidation to produce lorazepam-glucuronide.
Alprazolam: Uses, Dosage, Side Effects - Drugs.com
2023年8月23日 · Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that it works by enhancing the activity of certain neurotransmitters in the brain. Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.
What Did My Patient Actually Take? An Overview of ...
False negative immunoassay results may also occur due to failure of the assay to react to drug-specific markers such as alpha-OH-alprazolam, 7-aminoclonazepam, 2-hydroxyethylflurazepam, and lorazepam glucuronide. 6,11,12,16,18-21. At Aegis, we understand your concerns as you evaluate definitive drug testing results.
alpha-Hydroxyalprazolam | C17H13ClN4O | CID 162244
alpha-Hydroxyalprazolam | C17H13ClN4O | CID 162244 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
'New/Designer Benzodiazepines': An Analysis of the ...
Results. First designer BZDs appeared as NPS around 2007. So far, 29 designer BZDs have been notified to the EMCDDA, being some of them extremely powerful, also at lower dosages. They are sold as tablets/powder/pellets/capsules/blotters/liquids, at very affordable prices, and variably administered.
Clinical Pharmacology, Clinical Efficacy, and Behavioral Toxicity …
Alprazolam is a benzodiazepine derivative that is currently used in the treatment of generalized anxiety, panic attacks with or without agoraphobia, and depression. Alprazolam has a fast onset of symptom relief (within the first week); it is unlikely to produce dependency or abuse. No tolerance to its therapeutic effect has been reported.
Metabolite alpha-Hydroxyalprazolam - DrugBank Online
IUPAC Name. {12-chloro-9-phenyl-2,4,5,8-tetraazatricyclo [8.4.0.0^ {2,6}]tetradeca-1 (10),3,5,8,11,13-hexaen-3-yl}methanol. SMILES. OCC1=NN=C2CN=C (C3=CC=CC=C3)C3=CC (Cl)=CC=C3N12. Reactions. Alprazolam alpha-Hydroxyalprazolam.