Acyl-CoA dehydrogenase - Wikipedia
Acyl-CoA dehydrogenases (ACADs) are a class of enzymes that function to catalyze the initial step in each cycle of fatty acid β-oxidation in the mitochondria of cells. Their action results in the introduction of a trans double-bond between C2 (α) and …
MCAD deficiency - Symptoms and causes - Mayo Clinic
2023年11月28日 · Medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency is an inherited disorder that prevents your body from breaking down certain fats and turning them into energy. Your metabolism involves the processes your body uses to produce energy.
Acyl-CoA dehydrogenases: Dynamic history of protein family ...
The acyl-CoA dehydrogenases (ACADs) are enzymes that catalyze the alpha,beta-dehydrogenation of acyl-CoA esters in fatty acid and amino acid catabolism. Eleven ACADs are now recognized in the sequenced human genome, and several homologs have been reported from bacteria, fungi, plants, and nematodes. …
Acyl CoA Dehydrogenase - an overview | ScienceDirect Topics
Members of the acyl CoA dehydrogenase enzyme family catalyze analogous chemical reactions yet are distinguished by their unique substrate specificities.
Medium-Chain Acyl-CoA Dehydrogenase Deficiency
2024年2月29日 · Medium-chain acyl-CoA dehydrogenase (MCAD) catalyzes the mitochondria's first step of medium-chain fatty acid oxidation. MCADD is an autosomal recessive disorder caused by mutations in the acyl-CoA dehydrogenase medium chain (ACADM) gene.
Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency
2000年4月20日 · A survey of the newborn populations in Belgium, Germany, Poland, Czech Republic, Hungary, Bulgaria, Spain, Turkey, and Japan for the G985 variant allele with haplotype analysis at the medium chain Acyl-CoA dehydrogenase gene …
MCAD deficiency - Diagnosis and treatment - Mayo Clinic
2023年11月28日 · Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency full gene analysis. Mayo Clinic Laboratories. https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/35478. Accessed Feb. 2, 2022. Anderson DR, et al. Clinical and biochemical outcomes of patients with medium-chain acyl-CoA dehydrogenase deficiency.