2023年10月31日 · Isabella I of Castile (1451-1504), was Queen of Castile (r. 1474-1504) and of Aragon (r. 1479-1504) alongside her husband Ferdinand II of Aragon (1452-1516). Her reign included the unification of Spain, the reconquest of Granada, sponsoring Christopher Columbus in his voyage to explore the Caribbean, and the establishment of the Spanish Inquisition. ...