Short Stature (Growth Disorders) in Children - Yale Medicine
Short stature for which there is no underlying cause (called "idiopathic short stature") is defined by the U.S. Food and Drug Administration (FDA) as when a child's height is two standard deviations from the mean or when the predicted height.
Idiopathic short stature - Wikipedia
Idiopathic short stature (ISS) refers to extreme short stature that does not have a diagnostic explanation (idiopathic designates a condition that is unexplained or not understood) after an ordinary growth evaluation. The term has been in use since at least 1975 [1] without a precise percentile or statistical definition of "extreme".
Growth hormone treatment for idiopathic short stature
2023年11月22日 · Treatment of children and adolescents with recombinant human growth hormone (rhGH) for idiopathic short stature (ISS) is controversial for two reasons.
Short Stature - StatPearls - NCBI Bookshelf
2023年3月13日 · In literature, various terminologies are used to describe short stature based on the cause. These include idiopathic short stature, familial short stature, constitutional short stature, constitutional delay of growth, adolescence (CDGA), etc.
Controversies in the Definition and Treatment of Idiopathic Short ...
The term idiopathic short stature (ISS) refers to short children with no identifiable disorder of the growth hormone (GH)/insulin like growth factor (IGF) axis and no other endocrine, genetic or organ system disorder.
When to Be Concerned About Short Stature in Children: A Q&A …
2022年2月2日 · Idiopathic short stature is short stature with no identifiable etiology in an otherwise healthy child. Height is more than 2.25 standard deviations below the mean for sex and age, and bone age is normal, predicting a short adult height.
Idiopathic short stature: definition, epidemiology, and diagnostic ...
Idiopathic short stature is a condition in which the height of the individual is more than 2 SD below the corresponding mean height for a given age, sex and population, in whom no identifiable disorder is present.
Short Stature - Johns Hopkins Medicine
Short stature typically means that a person's height is below that of the shortest 3 percent to 5 percent of children of the same age and sex. Short stature could be idiopathic (with no known cause), an inherited trait or a symptom of one of a number of underlying disorders.
Idiopathic Short Stature | New England Journal of Medicine
2006年6月15日 · Idiopathic short stature, also referred to as normal-variant short stature or short stature of undefined cause, is a diagnosis of exclusion.
Deciphering short stature in children - PMC - PubMed Central …
Idiopathic short stature (ISS) has no identifiable causes, but children with this diagnosis are characterized by height more than 2 SDS below the mean height for age, sex, and population without any genetic, endocrine, systemic, or nutritional alterations, and includes the diagnoses of FSS and CDGP .