A Compendium of Intralesional Therapies in Nail Disorders
Intramatricial therapy (nail matrix injections) This involves direct administration of the drug into the nail matrix area. Indications. Dermatoses affecting the germinative nail matrix, e.g., nail psoriasis, nail lichen planus and trachyonychia. The nail changes which suggest the need for treating nail matrix are summarised in Table 4.
Recommendations for the definition, evaluation, and treatment of nail ...
In adult patients with nail psoriasis exclusively and few-nail disease with involvement of both the nail matrix and bed, the first-line treatment should be intralesional steroid injections and/or vitamin D analogues in combination with topical steroids.
What is nail psoriasis, and how can I treat it? - American Academy …
2023年2月15日 — Injections of corticosteroids (or another psoriasis medication): These injections can effectively treat the buildup under your nails, nail ridges, thickening nails, and separating nails (when the nail lifts up from the fingers or toes). Your dermatologist will inject this medication directly into or near your nails with signs of nail psoriasis.
Intralesional injection - DermNet
An intralesional injection is the direct injection of a therapeutic substance into a lesion or into the skin. The aim of an intralesional injection is to deliver a high concentration of medicine into the site of the pathology to maximise efficacy while minimising systemic adverse effects of the drug.
Nail Psoriasis: A Review of Effective Therapies and …
First-line treatments for few-nail disease (≤ 3 nails involved) includes topicals and intralesional injections. When disease involves > 3 nails, has extensive cutaneous and joint involvement, and has a significant impact on QoL, systemic therapies should be considered.
International Journal of Dermatology and Venereology
For psoriasis affecting the nail matrix only, the recommended first-line treatment is intralesional steroid injections through the proximal nail fold; 3 the injection of triamcinolone acetonide (maximum of 0.1-0.5 mL every 4-8 weeks) is still the most common method.
Optimal diagnosis and management of common nail disorders
If both nail matrix and bed are involved, intralesional injections and/or vitamin D analogues with topical steroids are the treatments of choice. Systemic treatment is generally reserved for patients with ≥3 nails affected, extensive skin psoriasis, presence of psoriatic arthritis or when quality of life is severely impacted.
Nail Psoriasis: A Review of Effective Therapies and ... - Springer
2021年5月12日 — First-line treatments for few-nail disease (≤ 3 nails involved) includes topicals and intralesional injections. When disease involves > 3 nails, has extensive cutaneous and joint involvement, and has a significant impact on QoL, systemic therapies should be considered
Treatment of Nail Psoriasis - Dermatologic Clinics
2024年3月9日 — Available therapies for nail psoriasis include intralesional, topical, and systemic agents, with treatment dichotomized based on few-nail (≤3 nails) and multiple-nail (>3 nails) disease. •. Intralesional steroid injections is first-line therapy for …
Treatment of Nail Psoriasis: Common Concepts and New Trends
2013年5月13日 — Injections to the proximal nail fold with 28- and 29-gauge needle syringes or with needle-less injectors are very effective in treating nail matrix disease such as pitting or ridging [1, 9, 36]. Up to 70–90% of psoriatic patients with both nail matrix and nail bed lesions respond to intralesional steroids, except for onycholysis, which shows ...