Genetic study provides evidence that alcohol accelerates biological aging
2022年7月26日 · Today, researchers from Oxford Population Health have published results from a new genetic-based analysis which suggest that alcohol directly accelerates aging by damaging DNA in telomeres. The findings are published today in Molecular Psychiatry. Telomeres are repetitive DNA sequences that cap the end of chromosomes, protecting them from damage.
Evaluation and Management of Alcohol use Disorder among …
A systematic review of 9 studies that included 6353 patients found that the Alcohol Use Disorders Identification Test (AUDIT) was useful for screening for hazardous alcohol use in patients older than 60 years, and that the CAGE questionnaire was helpful in screening for alcohol dependence .
Prevention and Screening of Unhealthy Substance Use by Older …
The Michigan Alcohol Screening Test-Geriatric Version (MAST-G) 63 is the first instrument specifically designed to identify drinking problems among older adults. The MAST-G has 24 yes/no questions with 5 or more positive responses indicating problematic alcohol use.
Alcohol consumption and telomere length: Mendelian ... - Nature
2022年7月26日 · Abstract. Alcohol’s impact on telomere length, a proposed marker of biological aging, is unclear. We performed the largest observational study to date (in n = 245,354 UK Biobank participants)...
Epigenetic aging is accelerated in alcohol use disorder and …
2019年8月29日 · We evaluated the effects of heavy, chronic alcohol consumption on epigenetic age acceleration (EAA) using clinical biomarkers, including liver function test enzymes (LFTs) and clinical measures.
Screening Older Adults for Alcohol Use - ScienceDirect
2023年1月1日 · Geriatric screening tools take into account the particular features of alcohol use in older adults, but minimal research and guidance are available regarding the best method for screening. Lack of knowledge and time are significant obstacles to adequate assessment.
Biological aging markers in blood and brain tissue indicate age ...
2024年1月26日 · Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder. Lea Zillich, Metin Cetin, Elisabeth M. Hummel, Eric Poisel, Gabriel R. Fries, Josef Frank, Fabian Streit, Jerome C. Foo, Lea Sirignano, Marion M. Friske … See all authors. First published: 26 January 2024. https://doi.org/10.1111/acer.15241.
Screening Older Adults for Alcohol Use - The Journal for Nurse ...
2022年9月22日 · •. Research and guidance on best practices for screening are limited. •. Traditional tools may not accurately assess older people. •. Alcohol screening should be performed regardless of the method. Abstract. The number of older adults engaging in unhealthy alcohol use is on the rise, and this trend is expected to continue as the population ages.
Quantitative neurobiological evidence for accelerated brain aging …
2017年12月11日 · Together, these results provide strong evidence for an accelerated aging model of AD and indicate an elevated risk of alcohol-related brain aging in elderly individuals.
What Alcohol Can Do to Your Biological Age - Northwestern …
Research examining the impact of alcohol consumption over a long period of time, as well as binge drinking, on biological aging has been limited. Overall, the investigators found significant associations between one lifespan-related marker of biological aging and the number of years you consume liquor and total alcohol, as well as the number of ...