Clinical review: Hemorrhagic shock | Critical Care | Full Text
2004年4月2日 — This review addresses the pathophysiology and treatment of hemorrhagic shock – a condition produced by rapid and significant loss of intravascular volume, which may lead sequentially to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage, and death. Hemorrhagic shock can be rapidly fatal. …
Traumatic Hemorrhagic Shock: Managing the Critical Factors of …
2020年10月10日 — Hemorrhagic shock is the major preventable cause of morbidity and mortality in patients suffering major trauma. 1 Hemorrhagic shock is defined as a form of hypovolemic shock in which severe traumatic blood loss leads to inadequate oxygen delivery to tissues. While the ultimate goal is definitive bleeding control, the resuscitative decisions up ...
Recognition of hypovolemic shock: using base deficit to think …
2013年3月13日 — Base deficit has frequently been utilized as an informal adjunct in the initial evaluation of trauma patients to assess the extent of their physiologic derangements. However, the current Advanced Trauma Life Support (ATLS) classification system for hypovolemic shock does not include base-deficit measurements and relies primarily on alterations in vital signs …
The European guideline on management of major bleeding and …
2023年3月1日 — Following the hypothesis that severe haemorrhagic shock is associated with a state of arginine vasopressin deficiency, Sims et al. performed a RCT in 100 trauma patients with haemorrhagic shock to assess the effect of supplementation of this hormone . This small but well-designed study showed that low-dose arginine vasopressin (bolus of 4 IU ...
Bench-to-bedside review: Latest results in hemorrhagic shock
2008年7月10日 — Hemorrhagic shock is a leading cause of death in trauma patients worldwide. Bleeding control, maintenance of tissue oxygenation with fluid resuscitation, coagulation support, and maintenance of normothermia remain mainstays of therapy for patients with hemorrhagic shock. Although now widely practised as standard in the USA and Europe, shock resuscitation …
Effects of different types of fluid resuscitation for hemorrhagic …
2015年12月1日 — Introduction Fluid resuscitation is an indispensable procedure in the acute management of hemorrhagic shock for restoring tissue perfusion, particularly microcirculation in splanchnic organs. Resuscitation fluids include crystalloids, hypertonic saline (HTS), and synthetic colloids, and their selection affects the recovery of microcirculatory blood flow and reactive …
The European guideline on management of major bleeding and …
2019年3月27日 — Background Severe traumatic injury continues to present challenges to healthcare systems around the world, and post-traumatic bleeding remains a leading cause of potentially preventable death among injured patients. Now in its fifth edition, this document aims to provide guidance on the management of major bleeding and coagulopathy following …
Hemorrhagic shock: a review | Critical Care | Full Text - BioMed …
2004年6月30日 — The treatment of hemorrhagic shock is addressed in the review, and mention is made of the main goals: to stop the source of hemorrhage and to restore the circulating volume. Conserving blood products, on the grounds of cost, restricted availability and their pathophysiological effects, is becoming a necessary shift in the approach to these ...
The acute management of trauma hemorrhage: a systematic …
2011年3月9日 — Introduction Worldwide, trauma is a leading cause of death and disability. Haemorrhage is responsible for up to 40% of trauma deaths. Recent strategies to improve mortality rates have focused on optimal methods of early hemorrhage control and correction of coagulopathy. We undertook a systematic review of randomized controlled trials (RCT) which …
Hemodynamic consequences of severe lactic acidosis in shock …
2015年4月9日 — Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these …