Thus, transcriptional ... kilobase) region of DNA, while, as described earlier, yeast have no enhancers but instead use one UAS sequence per gene, located upstream. Long-range regulation is ...

The Neilson Laboratory studies post-transcriptional regulation of gene expression in human diseases ... We are particularly interested in better defining how the 3' untranslated region of mRNA, and ...

Positive regulation by TFs that are activators is common in eukaryotes. Considering the restrictive transcriptional ground state, it is logical that positive regulation is the predominant form of ...