Figure 3. Butyrate ameliorates bone loss. OC and autoantibodies both contribute to bone erosion. Butyrate mitigates bone erosion by inhibiting TNF-α and the RANKL downstream factors TRAF6 and NFATc1, ...

The NLRP3 inflammasome is activated by various danger signals ... MyD88, myeloid differentiation primary response 88; IRAK4, IL-1 receptor-associated kinase-4; TRAF6, tumor necrosis factor receptor- ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Ventus Therapeutics US Inc. has divulged NLRP3 inflammasome inhibitors reported to be useful for the treatment of cancer, metabolic diseases, autoimmune diseases, and liver, renal, respiratory, ...

Michael Boyle is an experienced financial professional with more than 10 years working with financial planning, derivatives, equities, fixed income, project management, and analytics. Suzanne is a ...

When students become active doers of mathematics, the greatest gains of their mathematical thinking can be realized. The process of sense making begins when we create classrooms full of curious ...

Department of Gynecological Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P.R. China. *Corresponding Author: ...

Integral Youth Services has launched a groundbreaking app designed to empower the Klamath Community.

The term "alert and oriented" (AO) is a medical notation describing a person's level of consciousness and cognition (the ability to understand and learn through thought, experiences, and the senses).

The use of "anno domini" and "before Christ" to mark time began in the early days of Christianity, and they're still used to track calendar years today. When reading historical texts or delving ...