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网络毒理学+分子对接+乳酸化+实验机制解析!!!
为了预测BDE-47的结合位点和蛋白质结构,进行了分子对接。经过这一筛选步骤后,还剩下6个基因。对接结果显示,AOX1、PIK3R1、FGF2、CAV2、CYP2E1和TOP2A的对接得分相对较高,BDE-47通过H键与这些蛋白残基紧密结合(图5A- ...
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