At the heart of a renaissance in lipid biochemistry, systems biology is being used to define ... of lipids was one of extreme diversity in structure, number and biochemical utility.

Membrane lipids, once simply regarded as the constituents ... the rapidly expanding field of phosphoinositide biochemistry and biology. With an emphasis on signal transduction, it covers several ...

Lipids include fats (solid at room temperature) and oils (liquid at room temperature). Lipids are an important part of a healthy diet. The body uses lipids as an energy store, as insulation and to ...

Lipids include fats (solid at room temperature) and oils (liquid at room temperature). Lipids are an important part of a healthy diet. The body uses lipids as an energy store, as insulation and to ...

Lipids, or fats, are essential to life. They form the membranes around cells, protecting them from the outside. In nature, ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ...

By using biochemistry of lipids, cellular biology, microscopy and animal models we identified various interactions between lipids and chloride co-transporters crucial for their functionality and ...

To enhance mRNA distribution, Penn engineers have created an ideal “recipe” for ionizable lipids, which are essential ...

With it, the Penn team achieved the stepwise optimization of ionizable lipid structure, a feat that hadn’t been achieved previously, despite the application of rational design and combinatorial ...

Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, ...

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...