Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, ...

To report the third case of subacute cerebellar ataxia associated with metabotropic glutamate receptor type 1 autoantibodies (mGluR1-Abs), an uncommon syndrome known to be part of the group of ...

Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open ...

Finally, the SSRI-induced increase in serotonin concentration potentially impacts numerous serotonin receptor subtypes ... and inhibitory, ionotropic and metabotropic, and different second ...

In general, understanding these dynamics can provide insight into potential therapeutic targets and aid in drug discovery for these patients. In addition to GPR84, another G protein-coupled receptor ...

We found that both forms of t-LTD are expressed presynaptically and that whereas t-LTD at LPP-GC synapses does not require NMDAR, t-LTD at MPP-GC synapses requires ionotropic NMDAR containing GluN2A ...

Adenosine and various adenosine receptor ligands acting at adenosine A 1 and A 2A receptors have been explored in several experimental models of drug addiction. The therapeutic effects of the ...