Differentially expressed circFKBP8(5S,6) is a circular RNA with coding potential identified in control volunteers and patients with major depressive disorder (MDD). cFKBP8 is the protein encoded ...

Zhang’s team examined the molecular machine responsible for making this type of modification to the mRNA. They found that the protein Serrate interacts with this molecular machine to keep a disordered ...

A study now identifies, for the first time, hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the human brain.

In this useful study, a solid machine learning approach based on a broad set of systems to predict the R2 relaxation rates of residues in intrinsically disordered proteins (IDPs) is described. The ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Modulating the function of Intrinsically Disordered Proteins (IDPs) with small ...

Researchers find disordered protein segments are involved in gene expression, which could have implications in how cancer and neurodegenerative diseases are treated. Researchers from the Baylor ...

These microreactors can also selectively recruit phosphorylated proteins, providing insights into the evolution of enzymatic activity. The properties of biomolecular condensates can be regulated ...

Our observations reveal similarities between P granules and stress granules and identify intrinsically-disordered proteins as drivers of RNA condensation during P granule assembly. In this study, we ...

We are grateful to Drs. Ivet Bahar, Jeffrey Brodsky, and George Makhatadze for valuable comments and suggestions on the manuscript. This work was partially supported ...