$3.9 billion was wiped off Sepracor's market capitalization as investors called into question the entire utility of single enantiomers as a means of improving drugs and managing product life cycles.
The results are important because, while the left- and right-handed versions, or enantiomers, of chemical compounds have identical chemical properties, they differ in how they react in the human body.
Indivior is developing arbaclofen placarbil, a novel transported prodrug of ( R)-baclofen, the more active of the two baclofen enantiomers, for the treatment of alcohol use disorder. In ...
Nearly 56% of all modern drugs and medicine are chiral in nature, and about 90% of those are a mixture containing equal amounts of two enantiomers of a chiral compound. Researchers often face the ...
Just as left and right hands cannot be perfectly aligned through any combination of translations and rotations, these mirror-image forms, known as enantiomers, are identical in composition but ...
A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of “mir ...