They hope the discovery will now lead to new, effective therapies for people with some autoimmune and infectious diseases.Researchers have found that a natural metabolite called Itaconate can ...

Co-lead author, Christian Peace, from Trinity's School of Biochemistry and Immunology, based in TBSI, added, "Itaconate is a fascinating molecule made by macrophages during infections. It's ...

Luke O’Neill and his team have found that a natural metabolite called Itaconate can stimulate immune cells to make interferons by blocking an enzyme called SDH. Co-lead author, Shane O’Carroll ...

Published this week in the leading journal Nature Metabolism, Prof. Luke O’Neill and his team have found that a natural metabolite called Itaconate can stimulate immune cells to make interferons by ...

Macrophages, a population of immune cells in the lungs, are involved in this inflammatory process. Itaconate is a molecule with potential anti-inflammatory effects, produced by mammalian cells ...