They hope the discovery will now lead to new, effective therapies for people with some autoimmune and infectious diseases.Researchers have found that a natural metabolite called Itaconate can ...

Luke O’Neill and his team have found that a natural metabolite called Itaconate can stimulate immune cells to make interferons by blocking an enzyme called SDH. Co-lead author, Shane O’Carroll ...

Co-lead author, Christian Peace, from Trinity's School of Biochemistry and Immunology, based in TBSI, added, "Itaconate is a fascinating molecule made by macrophages during infections. It's ...