The first study evaluated the ability of NUZ-001 and its major active metabolite (NUZ-001 Sulfone) to reduce TDP-43 aggregation in M337V Motor Neurons co-cultured with astrocytes in response to a ...
Two separate preclinical studies were conducted in collaboration with Ncardia, a leading human induced pluripotent stem cell (iPSC) technology company. The first study evaluated the ability of NUZ-001 ...
Researchers have discovered that the NMDA receptor (NMDAR), known for its role in learning and memory, also stabilizes brain activity by setting baseline neural network activity.
Dr. Antonella Ruggiero studied NMDAR function in cultured neurons using an innovative technique called "dual perturbation," developed in Prof. Slutsky's lab. "First, I exposed neurons to ketamine, a ...
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