A new study reveals how interneurons, brain cells that regulate the firing of other neurons, act as traffic controllers in the hippocampus, a region critical for learning and memory.

"All interneuron" KOs exhibit deficits in synaptic transmission and interneuron excitability, not seen in excitatory neuron-specific KOs. Finally, they rescue the defects in the interneuron-specific ...

Researchers have developed the most detailed 3D computational models of key brain regions, including the hippocampus and ...

We found that neurons in the claustrum communicate with each other across efferent projection-defined modules which were differentially innervated by sensory and frontal cortical areas. Individual ...

Researchers have created a highly detailed cellular map of Alzheimer’s disease progression, revealing new insights into the ...

Department of Psychiatry and Behavioral Science, Kanazawa University Graduate School of Medical Sciences, Kanazawa, 920-8640, Japan Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, ...

Methods: Data were prospectively collected from 77 subjects (age 67 (SD 8) years) with one morphological type of cataract. 34 had cortical, 21 had nuclear, and 21 had posterior subcapsular cataract.

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The diversity of interneurons in the central nervous system is striking. Only in the cortex, interneurons account for around 20% of all neurons; most of these cells are GABAergic and are ...