Transmembrane proteins are frequently the primary targets of antibody therapies. Located on the cell membrane, these proteins are readily accessible for antibodies to bind to in the extracellular ...

The endoplasmic reticulum (ER)-localized transmembrane proteins IRE1, PERK and ATF6 detect the load of unfolded protein in the lumen of the organelle, serving as stress receptors. They transduce ...

2012;46(7):1065-1075. Class III mutations occur in only a small percentage of patients with CF (2–3%). [1] These mutations are called gating mutations. The CFTR protein reaches the cell membrane ...

The authors suggest that the transmembrane channel/scramblase family proteins may have originally functioned as scramblases but lost this ... The pipette solution (external) contained 140 mM NaCl, 10 ...

Yes, you heard me right. While you won't hear me saying you should add this to your daily meal plan, the Golden Arches can occasionally provide a satisfying bite while offering some redeeming ...

A pivotal study published in Obesity Science & Practice investigated the effects of dietary modifications on weight loss. Over the span of a year, 22 participants attended 19 educational ...

Alector has significant cash reserves but faces high cash burn, with no immediate catalysts and uncertain prospects for its ...

Discover seven protein-rich plant-based foods that can help you achieve your health goals. From lentils and chickpeas to tofu and quinoa, these options offer a variety of flavors and nutrients to ...

The research was published Oct. 30 in Nature Communications. IFITM3 (pronounced I-fit-M-3, for interferon-induced ...

A high-protein diet helped me lose 35 pounds and stay in shape for six years. I use my '4/5' rule to hit my protein target without tracking. Staple foods like chicken, Greek yogurt, and chickpeas ...