Cancer cells evade immune detection by altering their ribosomes. This adaptation makes them less visible to the immune system, presenting a potential target for enhancing cancer treatment ...

uhnresearch.ca Objectives Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo mechanism of mTOR ...

Our cells contain thousands of proteins that have gone largely undetected and unstudied until recent years: these are variants of known proteins, which cells can make when their protein-building ...

The gradients were scanned at 260 nm to visualize the ribosomal species. Area under the curve was quantified to calculate the 60S:40S ratio to check for ribosome biogenesis defect. Cells were counted ...

Selective autophagy is induced mainly by damaged organelles (mitochondria, lysosomes, endoplasmic reticulum, ribosomes), aggregation proteins and invading bacteria ... type III phosphatidylinositol ...

5, and BQ.1. (C) We analyzed the expression of Delta compared to BA.4/BA.5 using the GSE235262 dataset. In Delta, the mTOR pathway was observed to regulate ribosome biogenesis, autophagy, and lipid ...

Department of Molecular Immunology, Beijing Institute of Basic Medical Sciences, Beijing, China Erythroid cells are the most abundant cells in the human body. In addition to their established function ...

Research progress of water-in-oil emulsion gelated with internal aqueous phase: gel factors, gel mechanism, application fields, and future direction of development.

Indeed, the use of a different autophagic inducer, the mTOR inhibitor rapamycin, resulted in the potentiation of neuronal activity assessed by calcium imaging but not of morphological parameters in KO ...