Clenbuterol is a drug used in some countries as a bronchodilator to make breathing easier but is perhaps better known as a banned performance-enhancing drug (PDE) used by bodybuilders and athletes to ...

uhnresearch.ca Objectives Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo mechanism of mTOR ...

Hyperglycemia, through insulin resistance, leads to reduced glucose uptake, activating various pathways, including the aldose reductase (AR) pathway, PI3K/AKT pathway, and mammalian target of ...

This important study describes a combination of in vitro and in vivo results implicating Dyrk1a in the regulation of mTOR. Strengths include the combination of cell and ... more confirmation of the ...

Various signaling pathways regulate pulmonary fibrosis, including the TGF-β, Notch, Wnt, Hedgehog, and mTOR pathways. Among these, the TGF-β pathway is extensively studied, while the Notch pathway has ...

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Valeri Barsegov, Ph.D., Department of Chemistry, University of Massachusetts Lowell Hwai-Chen Guo, Ph.D., Department of Chemistry, University of Massachusetts Lowell ...

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Summary and Introduction Clinical Application—Disease Entities Theoretical Framework for Therapy−The 'Steel Paradigm' Conclusion References Theoretical Framework for Therapy−The 'Steel ...

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