Autoimmune diseases are characterized by reduced immune tolerance to self-antigens, leading to abnormal immune responses, often accompanied by systemic chronic inflammation. Consequently, PANoptosis, ...

【导读】过度的DNA损伤，会触发各种类型的程序性细胞死亡（PCD），但DNA损伤诱导细胞死亡的调节机制尚不完全清楚。在这项研究中，团队报道了PANoptosis，一种协调的PCD通路，包括细胞焦亡、细胞凋亡和坏死性凋亡，被DNA损伤激活。2024年1 ...

(155), STING prevented autoimmune diseases by recruiting the E3 ligase TRIM 21 to promote IFI16 degradation via the ubiquitin-proteasome pathway in order to maintain the appropriate IFI16 protein ...

If you’re worried you might have gum disease, there’s a good reason for that. About half of U.S. adults have gum disease. It’s one of the most common reasons people see the dentist. Also called ...

Fifth disease, also known as erythema infectiosum, is a contagious viral illness caused by parvovirus B19. It is most common in children, but it can also affect adults. The main symptom of fifth ...

Oct. 30, 2024 — Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe ...

Cardiovascular disease is a group of conditions that affect your heart and blood vessels. It's sometimes also called heart disease. Conditions that affect your heart and blood vessels can include ...

癌症治疗中的毒副作用一直是患者面临的重大挑战之一。近期同济大学蔡振宇团队的研究揭示了ZBP1在化疗过程中扮演的重要角色，但我们不得不问：这种看似不相关的细胞死亡机制，如何在未来的癌症治疗中成为防火墙？ ZBP1，这个细胞内的“警报器”，能够 ...

Oct. 31, 2024 — Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called ...