No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

癌症治疗中的毒副作用一直是患者面临的重大挑战之一。近期同济大学蔡振宇团队的研究揭示了ZBP1在化疗过程中扮演的重要角色，但我们不得不问：这种看似不相关的细胞死亡机制，如何在未来的癌症治疗中成为防火墙？ ZBP1，这个细胞内的“警报器”，能够 ...

Deciding on antigen vs. antibody tests when choosing a COVID-19 test is easier when the definitions and their function are clear. These tests represent different ways you can check for SARS-CoV-2, the ...

2024年10月27日，同济大学医学院蔡振宇团队在期刊《Cell Death & Disease》上发表了题为“Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA ...

Taken together, ZBP1 plays a crucial role in host immunity against autoimmune diseases driven by its own nucleic acids. However, our current understanding of the interaction between ZBP1 and ...

Researchers at Fred Hutchinson Cancer Center, led by Dr. Julie McElrath, Director of the Vaccine and Infectious Disease Division, have found a new way to train our immune system to make antibodies ...

It is important to notice that, beyond cGAS/STING, mtDNA (and mtRNA) can activate a wide range of other inflammation pathways including NLRP3 inflammasome, RIG-I, TLR9, ZBP1 or IFI16, described in ...

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Pregnancy test sticks use monoclonal antibodies to tell if a woman is pregnant ...

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