Using this approach revealed a drug resistance feedback loop in high-grade serous ovarian cancer, suggesting that combining phosphatidylinositol 3-OH kinase, protein kinase B and mammalian target ...

近些年来，“基因魔剪”CRISPR/Cas9基因编辑系统的出现让科学家们拥有了能高效改写DNA的革命性工具。在此之后，哈佛大学刘如谦（David Liu）教授又提出了单碱基编辑工具，让人们能够在不切断双链DNA的情况下，对出错的单个碱基进行精准替换。