A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a ...

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically ...

Researchers hope findings will lead to new class of drugs for many different diseases for which proteolethargy is a common ...

Researchers have identified that G-quadruplexes promote harmful protein aggregation in neurodegenerative diseases. Blocking ...

The complex, a type of “protein chaperone” known as TRiC, helps fold thousands of human proteins: It was later found that about 10% of all our proteins pass through its barrel structure. All animals ...

Behold the Body. Electron microgram of a Biondi body shows a dense core surrounded by filaments that bind gold-labeled secondary antibody to TMEM239 (black dots). [Courtesy of Ghetti et al., 2024.] ...

Tau behaves abnormally in the brain in people with Alzheimer’s disease. This latest study points to a reason why.

Scientists at La Trobe University have created a world-first method to investigate "disordered" proteins in living cells, in ...

Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of Alzheimer's, offering insights that could advance our understanding of the ...

Scientists are using artificial intelligence and powerful computing to sculpt new molecules in an effort to treat disease.

The formidable goal of treating disease demands unwavering scientific rigor across a sprawling set of ... For decades, ...